|
KMID : 1025720140330030063
|
|
Journal of Dental Implant Research
2014 Volume.33 No. 3 p.63 ~ p.66
|
|
|
Bone tissue engineering with bioreactors
|
|
Jeon Jae-Yun
Chung Joo-Ryun
Shim Kwang-Sub
Park Chang-Joo
Hwang Kyung-Gyun
|
|
|
Abstract
|
|
|
|
Reconstruction and regeneration of segmental defects and the atrophic maxilla and mandible have been performed using various techniques. Traditionally, the concept of guided bone regeneration has required reconstruction with autogenous particulate bone graft. One of the disadvantages of the guided bone regeneration is that it needs additional surgery. Also, it has the limitation of processing allogenic and heterogenic bone, not including bone-forming cells. The investigation of reconstructing defects using tissue-engineering utilizes the convergence of engineering and basic research advances in life science to solve the limitations. For tissue transplantation, bone-forming cells which make up the tissue to be able to form a bone carrier (scaffold), growth of inducing differentiation of a cell (cell), and the bone tissue for creating a bone tissue factor (growth factor) are required. And to require a system that can fuse these factors, it can be regarded as a bioreactor which enables three-dimensional culture system of these. Recently, development in tissue engineering and clinical attempts to deal with bioreactor have been actively proceeding. In this paper we are trying to study on bone tissue engineering around the bioreactor.
|
|
|
KEYWORD
|
|
|
Bone, Tissue engineering, Bioreactor
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
|
|